Research
Evidence reviews across peptides, GLP-1 medications, and longevity therapeutics. No secondary summaries — every claim traced to the trial, the label, or the paper of record.
Peptide evidence matrix
Every peptide graded by how strong the human evidence actually is — filter by tier, source on each grade.
GLP-1 weight-loss comparison
Every GLP-1 and incretin drug ranked by mean trial weight loss — filter, sort, tap through to the source.
9 reviews
- Evidence
What is NAD⁺? The coenzyme, the claims, and what the trials actually show
NAD⁺ is a coenzyme every one of your cells already uses, and its levels fall with age. That much is settled. What raising it back up actually does for you is a very different question — and the answer explains why the cheapest form has the best evidence.
7 min read - Evidence
NAD⁺ benefits: what the trials measured, and the one they tested that did not appear
NAD⁺ is sold on energy, focus, sleep and slower aging. Here is what human trials have actually measured — including a randomized trial where NR did not alter cognition at all.
7 min read - Evidence
NMN vs NR vs NAD⁺: what the difference actually is, and which has the better evidence
NMN and NR are not alternatives to NAD⁺ — they are the two common routes to it. Here is what each has been shown to do in human trials, which has more evidence behind it, and why both beat an injection on cost and data.
6 min read - Formats
What are NAD⁺ injections? How the shot works, what it costs, and what it is legally
A NAD⁺ injection is a compounded preparation shipped to you by a telehealth prescriber. Here is what that means, what it costs, and how it compares with the cheaper format that has better evidence behind it.
6 min read - Formats
NAD⁺ dosage: the doses used in trials, and why no honest chart exists
There is no NAD⁺ injection dosage chart, because there are no outcome trials to build one from. Here are the doses researchers actually administered, what products actually state, and the question to ask before you pay.
6 min read - Evidence
NAD⁺ injections before and after: what those photos can and cannot tell you
Before-and-after galleries show one person, chosen by the seller, with nothing controlled. Here is what a photo can actually establish — and the outcomes that were measured when researchers ran real trials instead.
6 min read - Evidence
Does NAD⁺ help with weight loss? What one trial found, and why it is not the claim
A trial of an NMN product did record a reduction in body weight — as one line in a broad panel, over 28 days, in adults already at metabolic risk. Here is why that is not a weight-loss result, and what NAD⁺ is actually for.
5 min read - Evidence
Is NAD⁺ a peptide? No — and what that tells you about who is selling it
NAD⁺ is a dinucleotide coenzyme, not a peptide. Here is the actual difference, why the whole industry blurs it, and what a seller misclassifying its own product should tell you about the rest of its claims.
5 min read - Safety
NAD⁺ side effects: what the safety trials show, and where there are none
Oral NAD⁺ precursors have been through dedicated safety trials and were well tolerated. Injections and IV drips have no comparable evidence base at all — and that difference is the one worth understanding before you choose a format.
6 min read